Concentrated-Platelet Rich Fibrin & Osopia
Concentrated Platelet Rich Fibrin (C-PRF) is the latest generation of Regenerative Blood Concentrates directly from research by Dr. Rick Miron of Jupiter, Florida. Dr. Miron's ground breaking research has led to new protocols that are sweeping the world of Regenerative Medicine. Dr. Miron is the author of the most cited article of the year, 2024, in the number one Dental journal (Periodontology 2000) related to his work on Platelet Rich Fibrin.
https://drive.google.com/file/d/1fuQUnBbiw9ZysyDY5IV2yIDSYwY8_h-4/view
I have had the privilege of training with Dr. Miron in Vancouver in 2022 and hands on instruction in Jupiter, Florida in the Advanced PRF Education in Facial Aesthetics at his clinic, in Dec 2023.
We are now using Dr. Miron's protocols for all our PRF treatments and I'm training dentists in my Vancouver Island PRF study club to use the same techniques.
Osopia is a synthetic Biphasic Calcium Phosphate (BCP) graft material manufactured using 3DI Surface technology. Its indicated for use in the specific treatment of extraction sockets and maxillary augmentation procedures.
Below is a YouTube link demonstrating the technique and some literature for those who maybe interested.
https://youtu.be/3OmIo_IrxQs?si=CIkpZX_7Wzp_P_AB
Miron RJ, Sculean A, Shuang Y, Bosshardt DD, Gruber R, Buser D, Chandad F, Zhang Y.Osteoinductive potential of a novel biphasic calcium phosphate bone graft in comparison with autographs, xenografts, and DFDBA. Clin Oral Implants Res. 2016 Jun;27(6):668-75. doi: 10.1111/clr.12647. (IF = 3.624)
Miron RJ, Shuang Y, Bosshardt DD, Caballé-Serrano J, Chandad F,Zhang Y. Osteogenic gene array of osteoblasts cultured on a novel osteoinductive biphasic calcium phosphate bone grafting material. Clin Oral Investig. 2017 Apr;21(3):801-808. doi: 10.1007/s00784-016-1825-0. Epub 2016 Apr 23. (IF = 2.308)
Miron RJ, Zhang Q, Sculean A, Buser D, Pippenger BE, Dard M, Shirakata Y, Chandad F, Zhang Y.Osteoinductive potential of 4 commonly employed bone grafts. Clin Oral Investig. 2016 Nov;20(8):2259-2265. (IF = 2.308)
Zhang Y, Shuang Y, Zhou W, Fu H, Qian L, Miron RJ. Addition of a synthetically fabricated osteoinductive biphasic calcium phosphate bone graft to BMP2 improves new bone formation. Clin Implant Dent Relat Res. 2016 Dec;18(6):1238-1247. doi: 10.1111/cid.12384. Epub 2015 Oct 28. (IF = 2.939)
Miron RJ, Zhang Y. The Arrival of Synthetic Bone Grafts with Osteoinductive Potential. J J Dent Res. 2014, 1(1): 002.
Barroso-Panella A, Gargallo-Albiol J, Hérnandez-Alfaro F Evaluation of Bone Stability and Esthetic Results After Immediate Implant Placement Using a Novel Synthetic Bone Substitute in the Anterior Zone: Results After 12 Months. Int J Periodontics Restorative Dent. 2018 Mar/Apr;38(2):235-243. doi: 10.11607/prd.2863.
